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Low Dose Naltroxene Therapy

An Innovative Option for Autoimmune, Inflammatory & Chronic Conditions
 

Low Dose Naltrexone (LDN) is a compounded prescription therapy that’s gaining recognition for its ability to modulate the immune system, reduce inflammation, and help manage a wide range of chronic conditions.
 

At doses much lower than its original use for addiction treatment, LDN acts on the body’s endorphin and immune regulation systems, helping restore balance in people dealing with autoimmune disease, chronic pain, and inflammation.

How does LDN work?

LDN works by briefly blocking opioid receptors in the body, which paradoxically causes a rebound increase in natural endorphins (feel-good hormones). This helps regulate immune responses and reduce inflammation at a cellular level.

It’s a gentle, well-tolerated therapy that works with your body’s own healing systems—without the immune suppression or harsh side effects often seen in conventional treatments.

How Low Dose Naltrexone (LDN) Works in the Body

  • LDN supports your body’s natural immune system and helps reduce inflammation by working with your body’s own healing chemistry

    🧠 Boosts Endorphins & Immune Function

  • LDN gently blocks your body’s opioid receptors for a short period. In response, your body increases the production of endorphins—your natural feel-good and pain-relieving chemicals.

  • But endorphins don’t just affect mood—they also:

    • Help regulate the immune system

    • Support tissue repair and cell growth

    • Reduce pain and inflammation

  • By boosting endorphins, LDN may help balance your immune system and improve how your body responds to chronic conditions.

    🛡 Supports Natural Defenses Against Cell Overgrowth

  • LDN interacts with something called the opioid growth factor (OGF) system, which plays a role in cell growth regulation.
    This means LDN may help slow down abnormal or excessive cell growth, which is why it’s being researched in areas like cancer support and autoimmune conditions.

    🔥 Calms Inflammation in the Nervous System

  • LDN also helps quiet down chronic nerve inflammation. When inflammation is ongoing, immune cells in the nervous system (called glial cells) can become overactive—amplifying pain signals and making symptoms worse.

  • LDN works by calming these glial cells, helping to reduce nerve sensitivity, ease pain, and support a healthier nervous system response.

FAQs

How Do I Start LDN?

  1. Book a virtual consultation with our Nurse Practitioner

  2. Medical assessment & prescription sent to a compounding pharmacy

  3. Ongoing support and follow-up to monitor your progress

LDN is typically started at low doses (0.5–1.5mg) and gradually increased based on your condition and response.

Is LDN Safe?

LDN is generally very well tolerated, with few side effects. The most commonly reported are vivid dreams or sleep disturbances early on, which often resolve. It’s non-addictive, non-suppressive, and has been used off-label for chronic conditions for decades.

Benefits and Uses of LDN Therapy
​

  • Autoimmune Diseases: LDN is used to modulate immune response and reduce inflammation in autoimmune disorders such as rheumatoid arthritis, lupus, Hashimoto's thyroiditis, and multiple sclerosis.

  • Cancer: Research suggests LDN may enhance immune function, reduce inflammation and have anti-cancer properties, potentially supporting conventional cancer treatments.

  • Chronic Fatigue Syndrome (CFS) / Fibromyalgia: LDN is used to alleviate symptoms of chronic fatigue and fibromyalgia by reducing inflammation and improving immune function.

  • Irritable Bowel Disorders (IBD): LDN has been explored as a treatment for inflammatory bowel diseases like Crohn's disease and ulcerative colitis, aiming to reduce inflammation and symptoms.

  • Hay Fever / Severe Allergies: LDN may help modulate immune responses involved in allergic reactions, potentially reducing symptoms of hay fever and severe allergies.

  • Lyme Disease: LDN is sometimes used in Lyme disease treatment protocols to manage symptoms and support immune function.

  • Multiple Sclerosis (MS): LDN has shown promise in reducing symptoms and slowing disease progression in some patients with multiple sclerosis.

  • Parkinson's Disease: LDN may have neuroprotective effects and help manage symptoms associated with Parkinson's disease.

  • Thyroid Disorders: LDN is used in thyroid disorders, including Hashimoto's thyroiditis, to modulate immune response and reduce inflammation affecting the thyroid gland.

  • Pain Reduction: LDN has shown effectiveness in reducing chronic pain associated with conditions such as fibromyalgia, autoimmune disorders, and neuropathic pain.

  • Mental Health Issues: There is emerging research on LDN's potential benefits for mental health conditions, including depression, anxiety, and mood disorders. Its mechanism of action may involve modulation of neuroimmune pathways.

  • Other Chronic Disorders: LDN is being investigated for its potential benefits in various chronic conditions where immune dysfunction and inflammation play a role.

Real Stories, Real Results

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A.J

"I had a fantastic experience at METALAB. The staff was welcoming and made me feel comfortable from the moment I walked in. Shelly was thorough, patient, and genuinely listened to my concerns. The clinic was clean and well-organized, and the appointment process was quick and efficient. I felt cared for every step of the way. Highly recommend to anyone looking for quality healthcare with a personal touch!"
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